What users are saying about
57 Ratings
<a href='https://www.trustradius.com/static/about-trustradius-scoring' target='_blank' rel='nofollow noopener'>trScore algorithm: Learn more.</a>Score 8.8 out of 100
Based on 57 reviews and ratings
16 Ratings
<a href='https://www.trustradius.com/static/about-trustradius-scoring' target='_blank' rel='nofollow noopener'>trScore algorithm: Learn more.</a>Score 8.2 out of 100
Based on 16 reviews and ratings
Feature Set Ratings
Endpoint Security
9.5
Microsoft Defender for Endpoint
95%
Palo Alto Networks Threat Protection
Feature Set Not Supported
N/A
Microsoft Defender for Endpoint ranks higher in 7/7 features
Microsoft Defender for Endpoint ranks higher in 7/7 features
Anti-Exploit Technology
9.3
93%
6 Ratings
N/A
0 Ratings
Endpoint Detection and Response (EDR)
9.6
96%
6 Ratings
N/A
0 Ratings
Centralized Management
9.6
96%
6 Ratings
N/A
0 Ratings
Hybrid Deployment Support
9.4
94%
5 Ratings
N/A
0 Ratings
Infection Remediation
9.3
93%
6 Ratings
N/A
0 Ratings
Vulnerability Management
9.6
96%
6 Ratings
N/A
0 Ratings
Malware Detection
9.6
96%
6 Ratings
N/A
0 Ratings
Attribute Ratings
- Microsoft Defender for Endpoint is rated higher in 1 area: Likelihood to Recommend
Likelihood to Recommend
9.0
Microsoft Defender for Endpoint
90%
8 Ratings
7.9
Palo Alto Networks Threat Protection
79%
4 Ratings
Support Rating
8.9
Microsoft Defender for Endpoint
89%
9 Ratings
Palo Alto Networks Threat Protection
N/A
0 Ratings
Likelihood to Recommend
Microsoft Defender for Endpoint
Small or large organizations will benefit from using MDE. They need to provide a way to buy MDE as a standalone add-on product not only make it a bundled feature in Microsoft 365 E5. I wish it had the ability to deploy updates to 3rd party apps when the vulnerability scanner discovers a vulnerability. Currently, I have to use a 3rd party tool to address this gap.
IT Director
Society of American FloristsNon-profit Organization Management, 11-50 employees
Palo Alto Networks Threat Protection
Palo Alto NTP is an appropriate suite of protection for any enterprise environment or anyone that truly needs some serious perimeter protection in a one-stop, all-in-one unit. There are no modules or add-ons or clunky interfaces to deal with it; everything works out of one management plane, licensing, implementation, monitoring. updating, etc. As a network admin, that is immensely valuable to me. Additionally, I get real-time reporting on all the stuff NTP is catching, and it is nothing to shirk at. The real value in NTP comes in only after you begin doing SSL-decryption, however, to truly inspect the traffic. Short of that, you are just seeing a bunch of encrypted data and the NTP suite of tools isn't going to avail you. NTP plus decryption, though, is invaluable!
Infrastructure , Network Administrator
Dynamic AviationAviation & Aerospace, 501-1000 employees
Pros
Microsoft Defender for Endpoint
- It is great at proactively monitoring threats across the network. It works seamlessly with the client to monitor individual user computers, and it has a good real-time scanning engine.
- On the client side, Windows Defender doesn't require a whole lot of system resources to run, nor will it create unnessary slowdowns of a computer, even while scanning for threats

Verified User
Supervisor in Information Technology
Education Management Company, 1001-5000 employeesPalo Alto Networks Threat Protection
- Anti virus
- Vulnerability protection
- Anti spyware
Presales
Network TechlabInformation Technology & Services, 501-1000 employees
Cons
Microsoft Defender for Endpoint
- Virus detection rates are below competitors.
- Too many notifications that end up bothering.
- Do not ask every time if you should send reports to Microsoft.
Performance e Controle Comercial na Groupe Renault
Groupe RenaultAutomotive, 10,001+ employees
Palo Alto Networks Threat Protection
- Sometimes I struggle to find the deny or specific traffic log for file blocking profile under Unified logs.
- Reporting around Threat Prevention suite could be much better.
- Possibly a specific threat prevention search function that spans across of threat features.

Verified User
Analyst in Information Technology
Financial Services Company, 1001-5000 employeesPricing Details
Microsoft Defender for Endpoint
General
Free Trial
—Free/Freemium Version
—Premium Consulting/Integration Services
—Entry-level set up fee?
No
Starting Price
$250 per user/per month
Microsoft Defender for Endpoint Editions & Modules
Edition
Standalone | 5.201 |
---|---|
Academic | 2.501 |
- per user/per month
Additional Pricing Details
—Palo Alto Networks Threat Protection
General
Free Trial
—Free/Freemium Version
—Premium Consulting/Integration Services
—Entry-level set up fee?
No
Starting Price
—Palo Alto Networks Threat Protection Editions & Modules
—
Additional Pricing Details
—Support Rating
Microsoft Defender for Endpoint
Microsoft Defender for Endpoint 8.9
Based on 9 answers
Every time I've had a question or a problem, I was able to get it addressed quickly. Microsoft has a huge database for ATP support, and it has contained 90% of what I have looked for. It was a lifesaver during initial setup.

Verified User
Technician in Information Technology
Education Management Company, 51-200 employeesPalo Alto Networks Threat Protection
No score
No answers yet
No answers on this topic
Alternatives Considered
Microsoft Defender for Endpoint
Defender works better for my org. This may depend on your ecosystem, however for me, Defender is a clear winner. I like Defender's ability to utilize multiple sensors and data points to detect possible breaches. I like the built-in EDR functionality. I do not need to purchase a separate EDR software anymore. I really like the vulnerability management. it has enabled our SOC team to view multiple security-related sensors from a single portal.
Senior Manager-Cyber Security
Brookfield RenewableEnvironmental Services, 1001-5000 employees
Palo Alto Networks Threat Protection
It is comparable but not as robust as other stand alone IPS/IDS.
Security Architect
Securicon, LLCComputer & Network Security, 11-50 employees
Return on Investment
Microsoft Defender for Endpoint
- There is definitely a piece of mind provided when you know that your system will not get compromised because of malware and viruses.
- The fact that I don't have to spend money in the first place means that I can spend money on other more important things that do require it.
Marketing Associate
Mercer-MettlInformation Technology and Services, 501-1000 employees
Palo Alto Networks Threat Protection
- We have various compliance standards we have to meet and the Palo Alto with its Networks Threat Protection suite has checked off pretty much all the boxes we needed and at a price point that couldn't be easily beat for comparable features, throughput, etc.
- IT/Network staff has saved a A LOT of time using this platform for protection (coming from an ASA)
Infrastructure , Network Administrator
Dynamic AviationAviation & Aerospace, 501-1000 employees