Accrisoft Freedom will free you from the worries of open source CMS tools.
It is the CMS that our website is built on. We partnered with Spinweb on our site build and Freedom is the CMS they use.
The only thing I believe Accrisoft Freedom is not as well suited is for large e-commerce sites. Accrisoft Freedom actually has an E-commerce module and can do products and online sales, however if this is the majority of what your business does (or your clients' businesses), I would recommend an E-commerce focused CMS.
For almost all other circumstances I can think of though, I would recommend Accrisoft Freedom - ma and pa shops on up to a corporation.