AppSense is used on all company owned Windows computers in our network, across all locations. We use it for software personalization and for doing some custom actions that would otherwise typically be done via logon script or group policy. For example, we use it to map printers for users based on their location and/or AD group membership. We also use Application Manager to automatically run some legacy software with admin rights. This happens transparently without the user having admin rights and without seeing a UAC prompt and is a very useful feature for any application that requires admin rights to run. It also allows users to self-install certain pre-approved applications while not giving them rights to install any random software.