Use Cases and Deployment Scope
We use it for a file share, but the first reason is for backup. We have many installations, even in the data center of our cloud provider. For backup Virtual Machine (usually snapshot) and for our Oracle and Sqlserver production databases. We use Smb, NFS, i-SCSI directly attached to the machine (for disk quorum cluster), and so far nothing to complain about.
Other Software Used
Oracle Database, Microsoft SQL Server, Veeam ONE