Microsoft's Azure Application Gateway is a platform-managed, scalable, and highly available application delivery controller as a service with integrated web application firewall.
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VMware NSX
Score 8.8 out of 10
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VMware NSX is network virtualization technology. VMware NSX is no longer sold as a standalone product and is now available as a part of VMware Cloud Foundation.
For building scalable and highly available applications, Azure Application Gateway does most of the job on behalf of you; automatically load-balancing traffic from a number of users to a number of back-end servers. This ensure scalability and availability. The in-built security is great as can be expected from Microsoft, and user has a variety of tools for monitoring the health of the load-balancing function as well as the health of back end servers behind it.
With proper design, VMware NSX can and should be deployed to virtually any VMware virtualization environment, but the deployment should be tailored to the needs of that environment. There isn't really a one size fits all deployment design for all environments. That versatility is what provides its greatest strength to a business.
Most of the Application Gateway's features and services can be managed and re-configured via either the Azure Portal GUI or via the Azure Cloud Shell, thus allowing both CLI modes, i.e. Azure CLI (Bash) and Azure Powershell. The v2 version of Application Gateway has significantly improved performance during initial configuration or during re-configuration changes, thus making it much more usable for IT admins, as compared to v1.
Other load balancing tools in Azure (Azure LB and Azure Traffic Manager) are limited in their functionality in comparison with the Azure Application Gateway, and also, they don't provide security features. Azure Firewall, although it has security features, is more expensive, and most importantly, it's not a load balancer at all.
We use both Cisco ACI and VMware NSX, and while they have different strengths and capabilities, I would recommend VMware NSX, as it can be used in all VMware environments, without costly physical infrastructure changes. Cisco ACI provides some of the same capabilities, but not all. It's focus relies on physical networking changes.