IBM Rational ClearCase might be better suited for a smaller / simpler code base. Larger code bases really slow it down... but then again there are better alternatives out there for source control
The Infrascale Platform solution we have in place is certainly not cheap - I believe we are paying about $2800/month for it, though it is quite robust. We have 18TB of on-site storage available, with the same available in a secondary - remote - device for replication. They do have a wide range of products available to any size business though, so I'm sure they have cheaper offerings as well. The on-site appliance is fantastic - in that in houses your backups, but can also be utilized as an emergency piece of hardware to spin up a backup and run it in the event of your primary hardware failing. You can also traverse full backups to grab single, contained, files if you so choose. We love that feature as we must perform file recovery monthly for audit purposes.
Rational ClearCase is excellent for handling versioning and branching. No other tool I've used has the depth that ClearCase has when it comes to handling complex branching scenarios and identifying where certain versions of particular files are within a particular configuration.
Rational ClearCase handles parallel development of many dependent applications really well.
The use of ClearCase Views to switch between projects and configurations is extremely convenient as opposed to the local workstation model of the competitors.
It is one of the best cloud back up data protection software and software platforms on the entire market for MSPs. There are not many other solutions that offer this level of customization and execution in the data protection and disaster recovery arena better than Infrascale. I highly recommend it for any MSP.
If development is centrallized to one location and your company releases hundreds of customized versions of your software per year, then ClearCase is the best tool for managing the complexity of multiple versions of customized software. If your company has globally distributed development, then I'd recommend Team Foundation Server over ClearCase. If your organization uses Agile Methodologies, then I'd recommend TFS with GIT.
Infrascale Platform is the most modern backup service/device we've utilized. EaseUs and Ghost were just software that would run within a Windows environment (at the time) and backup to a device that we kept on-site. EaseUs would fail quite often with Incremental backups - so I would spend a lot of time re-running full backups to ensure we didn't experience data loss in the event of a crash. Ghost was used when I was first hired at this district - so I didn't have much hands-on experience with it. But I know it was a bundled offering with Anti-Virus back when we utilized it ('07-'09ish).
Peace of mind: our entire virtual environment is backed up both onsite and offsite
As stated, it is pricey. Since we haven't needed to do anything more than basic file restores, ROI is hard to measure. A full restore of a virtual server immediately would be priceless. So, on that note, ROI is good.