Microsoft Project Server

Microsoft Project Server I believe is best for any organization from small to large. As I mentioned, it is a little pricey so I would do research into alternative software and depending on your needs maybe look at all options, competing software. This is a tool with a learning curve and some may not be able to easily navigate this software. There isn't really great training, resources available for this tool however there are some free YouTube tutorial videos. This is great for cross company, department project management, sharing, managing of projects and timelines.

You will be able to do the project management (scheduling, tasks assignment, resources allocation, cost tracking) for all your projects in one place, where the team members can contribute and keep the plans up to date. The web version does the main job right but if you find it more difficult to use you just use the standalone Microsoft Project and upload the changes back to the server.

Microsoft Project Server has proved to be well suited when managing simple projects without a ton of interdependencies and resourcing needs. It works well with managing forecast and baseline dates. The software is less appropriate when the scheduling needs are more complex. Although it does allow for collaboration amongst scheduling, budgeting, resourcing and risk analysis, it is probably not the best tool when those needs are complex.

Perhaps the greatest positive is the resource engagement and assignment, ensuring we are able to effectively plan the delivery of numerous projects, thus avoiding any duplicate bookings. On the flip side, once projects grow into very large plans with ultra-detailed assignments, it can become difficult to manage.

For project management it is very well suited, needs to figure out speed.

I think Microsoft Project server is probably better for larger companies - if you're only tracking a handful of projects, the cost may not be worth it if you have a faster/more cost efficient way of tracking project information. However, when you're trying to track many different projects across many different departments, then I think Microsoft Project server is very helpful. Same thing if you only have one person responsible for project information - it might be more cost efficient to track information another way. If you have many people collaborating on projects then Microsoft Project Server is great for having a unified source to pull project information.

Considering what new versions of project server (especially project online) provides out of the box and its smoother integration with Office 365, I would highly recommend exploring option of project server 2013 (or online). End of the day, whatever complex tools you use; you will end up doing something in office applications :). And project online being in the same office ecosystem (Office 365, Office applications, SharePoint) helps. Microsoft is aligned with mobile first and cloud first approach and this will ensure that your project online system remains up-to-date without any additional cost.

It is well suited for any type of project portfolio management scenario.